Agarose Gel Electrophoresis wa RNA

Kafukufuku watsopano kuchokera ku RNA

Posachedwapa, kafukufuku wapeza kuti mitundu yosiyanasiyana ya majinizomwe zimachepetsa milingo yosinthira ya RNA yokhala ndi mizere iwiri imalumikizidwa ndi autoimmune komanso chitetezo chamthupi.

Mamolekyu a RNA amatha kusinthidwa. Mwachitsanzo, ma nucleotide amatha kuyikidwa, kuchotsedwa, kapena kusinthidwa. Chimodzi mwa zosintha zodziwika bwino, zomwe kafukufuku watsopano akuwonetsa zimagwira ntchito yofunika kwambiri pakuyambika kwa matenda otupa, ndikusintha kwa nucleotide adenosine kukhala inosine mkati mwa RNA yamitundu iwiri. Phunziroanalizosindikizidwaon Ogasiti 3 mu Nature akuwonetsa kuti mitundu yosiyanasiyana ya majini yomwe imachepetsa kusinthidwa kumeneku kumalumikizidwa ndi chiwopsezo chowonjezereka cha matenda otupa omwe amayambitsa matenda a autoimmune komanso chitetezo chamthupi monga psoriasis, matumbo otupa, komanso mtundu woyamba wa shuga. Olembawo akuwonetsa kuti mapuloteni a sensor amatha kulakwitsa ma RNA osasinthidwa pang'ono a mamolekyu akunja, zomwe zimayambitsa kuyankha kwa kutupa.

Katswiri wa zamoyo za maselo ankaganiza choncho's kwenikweni chopambana chachikulu, ndipo anapeza"zodabwitsa kwambiri" momwe kusintha kwa RNA kumawonekera kukhala kofunikira pa matenda otupa, poyerekeza ndi mawonekedwe a jini kapena kuphatikizika.

Ndi kafukufuku wamkulu. Ndipo monga malonda ogulitsa ma electrophoresis, ndili ndi chidwi chofuna kudziwa kuti RNA ndi chiyani, komanso momwe asayansi amasanthula RNA ndi electrophoresis? Ndi chidziwitso chaukadaulo komanso chosadziwika bwino kwa ine komabe ndizosangalatsa kuzifufuza.

Kodi RNA ndi chiyani?

RNA, mwachidule kwa Ribonucleic acid, nucleic acid yomwe ilipo m'maselo onse amoyo. Mosiyana ndi DNA, RNA nthawi zambiri imakhala ndi chingwe chimodzi. Ntchito yake yayikulu ndikuchita ngati mthenga wonyamula malangizo ochokera ku DNA owongolera kaphatikizidwe ka mapuloteni, ngakhale kuti ma virus ena a RNA osati DNA amakhala ndi chidziwitso cha majini.

Agarose Gel Electrophoresis wa RNA

Anthu angathekuunika mtundu wa RNA ndi gel electrophoresis.

Beijing Liuyi Biotechnology Co.Ltd, awopanga akatswiri kuyang'ana pa electrophoresis mankhwala kwa zaka 50, amapereka osiyanasiyana akasinja electrophoresis (zipinda/maselo) kwa gel electrophoresis, monga yopingasa electrophoresis akasinja (zipinda/maselo) kwa agarose gel electrophoresis, ndi ofukula electrophoresis akasinja (zipinda/maselo) kwa puloteni gel electrophoresis. Pakadali pano, imaperekanso mitundu yosiyanasiyana yamagetsi a electrophoresis, nduna yamdima yamabokosi osanthula ndi UV transilluminator. Mukhoza kusankha Beijing Liuyi's akasinja a electrophoresis (zipinda/maselo) kuti ayeze kulemera kwa mamolekyu a RNA ndi kulekanitsa RNA ya makulidwe osiyanasiyana a labu yanu.

Apa tikuwonetsa mtundu umodzi wa tanki yopingasa ya electrophoresis (chipinda/selo) ya DYCP-31DN kuchokera pazogulitsa zathu 31.

DYCP-31DN ndi thanki yaing'ono yopingasa ya electrophoresis (chipinda/selo) yoyezera kulemera kwa maselo a RNA kapena DNA ndi kuwalekanitsa.